Indocyanine Green
Indocyanine green (ICG) is a cyanine dye used in medical diagnostics. It is used for determining cardiac output, hepatic function, liver and gastric blood flow, and for ophthalmic angiography It has a peak spectral absorption at about 800 nmThese infrared frequencies penetrate retinal layers, allowing ICG angiography to image deeper patterns of circulation than fluorescein angiography.ICG binds tightly to plasma proteins and becomes confined to the vascular system ICG has a half-life of 150 to 180 seconds and is removed from circulation exclusively by the liver to bile juice
Systematic name
sodium 4-[2-[(1E,3E,5E,7Z)-7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-2-ylidene]hepta-1,3,5-trienyl]-1,1-dimethylbenzo[e]indol-3-ium-3-yl]butane-1-sulfonate
Therapeutic category
Cardiac/Liver/Diagnostic
Available formulations
Injectable